methyl-beta-cyclodextrin
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Business Type:Manufacturer
Country/Region:China
Ddu Verified
HOT Rank
6/10
Shandong Binzhou Zhiyuan Bio-tech Co., Ltd.
We are professional supplier of hydroxypropyl cyclodextrin,sulfobutyl ether-beta-cyclodextrin sodium salt,methyl cyclodextrin,mercapto cyclodextrin,amino cyclodextrin,ethanediamine cyclodextrin,piroxi
Business Type:Manufacturer
Country/Region:China
Ddu Verified
HOT Rank
6/10
Name: methyl-beta-cyclodextrin
Other name : methyl-β-cyclodextrin
CAS: 128446-36-6
Abbreviation: MEBCD
Molecular formula : C42H70-nO35·(CH3)n
Molecular weight: 1135 + n•(14.0)
Standard : enterprise standard
Package: 500g/bag,1kg/bag, 10kg/drum or customized
Use : medical chemical other industries
Description
Appearance | white powder, insipid, innocent | Qualify |
Assay | ≥98% | 99.6% |
Degree of Substitution | 11.2-13.3 | 13.0 |
Molar of substitution | 1.6-1.9 | 1.8 |
Loss on Drying | ≤5.0% | 3.9% |
Optical density of a 10%solution (220-350nm) | ≤1.0 | Qualify |
Optical density of a 10%solution (350-600nm) | ≤0.1 | Qualify |
Chloride | ≤0.2% | ≤0.05% |
Unsubstituted cyclodextrin | ≤0.3% | Absent |
Residue on Ignition | ≤0.5% | 0.39% |
Heavy Metal (as pd) | ≤0.0001% | 0.0001% |
Arsenic salt (AS) | ≤0.0005% | 0.0005% |
Specific rotation | 154º-165º | 156.2º |
Solubility in water(25℃) | >750g/L | Qualify |
TAMC(cfu/g) | ≤1000 | 10 |
TYMC(cfu/g) | ≤100 | 10 |
Salmonella/E. Coli (cfu/g) | Absent | Absent |
Storage: at room temperature, in tightly closed container.
Characteristics and applications:
Methyl-beta-cyclodextrin is one of cyclodextrin derivatives that were widely used in modern researches and applications.
methyl-beta-cyclodextrin can be soluble both in water and in organic solvents. In pharmaceuticals industry, it can increase solubility and bioavailability of drugs, so that the efficacy of drugs can last longer with less ingestion. It can adjust and control the drug release rate, reduce drug side-effects, and enhance the stability of drugs particularly for oil-soluble molecules.
In commodity chemicals and cosmetics, can reduce microbial contamination and skin irritations, keep skin moist, mask bad odors, promote transdermal absorption of activeingredients.
methyl-beta-cyclodextrin has a larger surface tension in common cyclodextrin derivatives.