methyl-beta-cyclodextrin

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  • Min.Order:1 Kg(s)
  • Production Capacity:50000Kgs
  • Payment Terms:T/T
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Shandong Binzhou Zhiyuan Bio-tech Co., Ltd.

Business Type:Manufacturer

Country/Region:China

Ddu Verified

HOT Rank

6/10

Product Information

  • CAS:128446-36-6
  • Chemical Formula:C42H70-nO35·(CH3)n
  • Molecular Weight:1135 + n•(14.0)
  • Assay:99.6%
  • Pharmacopeia:USP
  • Package Type: 500g/bag,1kg/bag, 10kg/drum or customized
  • Shelf Life:18 months
  • Storage:Sealed
  • Place of Origin:china

Description

Name: methyl-beta-cyclodextrin 

Other name : methyl-β-cyclodextrin 

CAS: 128446-36-6

Abbreviation: MEBCD

Molecular formula : C42H70-nO35·(CH3)n

Molecular weight: 1135 + n•(14.0)

Standard : enterprise standard 

Package: 500g/bag,1kg/bag, 10kg/drum or customized

Use : medical  chemical  other industries

Description 

Appearance

white powder, insipid, innocent

Qualify

Assay

≥98%

99.6%

 Degree of    Substitution

11.2-13.3

13.0

Molar of substitution

1.6-1.9

1.8

Loss on Drying

≤5.0%

3.9%

Optical density of a 10%solution (220-350nm)

≤1.0

Qualify

Optical density of a 10%solution (350-600nm)

≤0.1

Qualify

Chloride

≤0.2%

≤0.05%

Unsubstituted cyclodextrin

≤0.3%

Absent

Residue on Ignition

≤0.5%

0.39%

Heavy Metal (as pd)

≤0.0001%

0.0001%

Arsenic salt (AS)

≤0.0005%

0.0005%

Specific rotation

154º-165º

156.2º

Solubility in water(25℃)

>750g/L

Qualify

TAMC(cfu/g)

≤1000

10

TYMC(cfu/g)

≤100

10

Salmonella/E. Coli (cfu/g)

Absent

Absent

Storage: at room temperature, in tightly closed container.

Characteristics and applications:

Methyl-beta-cyclodextrin is one of cyclodextrin derivatives that were widely used in modern researches and applications.

methyl-beta-cyclodextrin  can be soluble both in water and in organic solvents. In pharmaceuticals industry, it can increase solubility and bioavailability of drugs, so that the efficacy of drugs can last longer with less ingestion. It can adjust and control the drug release rate, reduce drug side-effects, and enhance the stability of drugs particularly for oil-soluble molecules.

In commodity chemicals and cosmetics,  can reduce microbial contamination and skin irritations, keep skin moist, mask bad odors, promote transdermal absorption of activeingredients.

methyl-beta-cyclodextrin has a larger surface tension in common cyclodextrin derivatives.


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